大肠肿瘤的发生过程是一个经过腺瘤阶段多阶段、多基因改变的过程,随着对肿瘤发生过程分子机制研究的不断深入,癌基因和抑癌基因的失活以及细胞增殖和凋亡的失衡在大肠肿瘤的研究领域成为近年来研究的热点。survivin,又称生存素,是新近发现的一种凋亡抑制基因,越来越多的研究表 The process of colorectal cancer is a multi-stage and multi-gene change process through the adenoma stage. With the further research on the molecular mechanism of tumorigenesis, the inactivation of oncogenes and tumor suppressor genes and the imbalance of cell proliferation and apoptosis In the field of colorectal cancer research has become a hot spot in recent years. Survivin, also called Survivin, is a recently discovered inhibitor of apoptosis, and more and more studies