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肺炎支原体(MP)是引起呼吸道感染的常见病原体之一,其病理常呈现毛细支气管炎样改变或间质性肺炎,临床表现以顽固性咳嗽为特征,引起的肺炎和肺外并发症对儿童健康危害较大。MP感染的治疗以抗生素为主,由于不规范用药,耐药菌株不断出现,一些常用治疗MP的抗生素疗效逐渐欠佳。近年来开发的新一代抗生素如大环内酯类、喹喏酮类等疗效好,不良反应少,一些中药方剂治疗MP疗效满意。作者对抗生素的使用、中药治疗等的作用机制及其临床治疗效果作一综述。
Mycoplasma pneumoniae (MP) is one of the common pathogens causing respiratory tract infection, the pathological changes often show bronchiolitis-like or interstitial pneumonia, clinical manifestations of intractable cough characterized by pneumonia and pulmonary complications caused by the health of children More harmful. The treatment of MP infection mainly antibiotics, due to non-standard medication, drug-resistant strains continue to appear, some of the commonly used antibiotics to treat MP gradually poor efficacy. In recent years, the development of a new generation of antibiotics such as macrolides, quinolones and other good efficacy, fewer adverse reactions, some of the traditional Chinese medicine treatment of MP satisfaction. The author summarizes the mechanism of action of antibiotics and traditional Chinese medicine treatment and its clinical effect.