慢性重度锰中毒以震颤麻痹为特点,主要病变发生在锥体外系基底神经节及中脑的黑质。慢性锰中毒患者在脱离接触后,如不积极治疗,病情仍可继续进展。本文报道1例慢性重度锰中毒患者反搏治疗前后血循环功能的改变及治疗效果。 一、病史摘要 张某,女,48岁,电焊工;1958年起从事含锰焊条电焊工作10年,常在通风不良的部位焊接;脱离接触后于1976年起渐感右侧肢体麻木、僵硬、震颤, Chronic severe manganese poisoning is characterized by Parkinsonism paralysis, the major lesion occurring in the extrapyramidal basal ganglia and midbrain substantia nigra. Chronic manganese poisoning in patients out of contact, if not actively treated, the disease can continue to progress. This paper reports a case of chronic severe manganese poisoning before and after counterpulsation in patients with changes in blood circulation and treatment effect. First, the medical history summary Zhang, female, 48 years old, welders; engaged in welding work of manganese electrode for 10 years since 1958, often welded in poorly ventilated parts; from 1976, gradually became sensible numbness on the right limb, stiff , Tremor,