Soil and water loss is now a major environmental problem in many areas of China, especially in the area of the Dabie Mountain, Anhui Province, which results in environmental degradation and does harm to the people’s life and production there. Based on the observational records from the Dasha River, the authors analyze the character of the variation in flow and sediment in different flood and dry seasons from 1970 to 2000. The result shows that human activities had significantly reduced the sediment discharge and sediment module, and increased the runoff in low-water seasons since the 1980s. The average contribution rate of human activities to decreasing sediment was 65.67%, and at the same period the contribution rate of runoff and rainfall was about 34.33%. Therefore, it is necessary to take the biological and engineering measures to solve the problem of soil and water loss in the Dasha River watershed. Soil and water loss is now a major environmental problem in many areas of China, especially in the area of ​​the Dabie Mountain, Anhui Province, which results in environmental degradation and does harm to the people’s life and production there. Based on the observational records from the Dasha River, the authors analyze the character of the variation in flow and sediment in different floods and dry seasons from 1970 to 2000. The result shows that human activities had significantly reduced the sediment discharge and sediment module, and increased the runoff in low- water seasons since the 1980s. The average contribution rate of human activities to sediment was 65.67%, and at the same period the contribution rate of runoff and rainfall was about 34.33%. Therefore, it is necessary to take the biological and engineering measures to solve the problem of soil and water loss in the Dasha River watershed.