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目的探讨和分析米非司酮联合米索前列醇在终止孕14～20周妊娠中的应用效果。方法通过本院5年来对孕14～20周妊娠的健康妇女应用米非司酮联合米索前列醇引产(观察组)与羊膜腔注射依沙吖啶引产(对照组)相比较。观察两组孕妇引产时间、产后出血量、清宫率、宫颈损伤等指标。结果对照组引产成功率为98.7%,对照组引产成功率为88.7%,两组引产成功率比较,差异有统计学意义(χ2=6.83,P<0.05)。两组孕妇总引产程、出血量、清宫率、宫颈损伤比例比较,差异均有统计学意义(P<0.05)。结论米非司酮联合米索前列醇与羊膜腔注射依沙吖啶两者用于中期妊娠引产相比较,米非司酮联合米索前列醇临床疗效较好。
Objective To investigate and analyze the effect of mifepristone combined with misoprostol in the termination of gestational pregnancy at 14 to 20 weeks. Methods Five-year pregnant women with pregnancy between 14 and 20 weeks were treated with mifepristone combined with misoprostol induction (observation group) and amniotic injection of ethacridine induced labor (control group). Two groups of pregnant women induction of labor time, postpartum hemorrhage, clearance rate, cervical injury and other indicators. Results The success rate of induction of labor was 98.7% in the control group and 88.7% in the control group. The difference between the two groups was statistically significant (χ2 = 6.83, P <0.05). The two groups of pregnant women total labor, bleeding, the rate of clear palace, the proportion of cervical injury, the difference was statistically significant (P <0.05). Conclusion Mifepristone combined with misoprostol and amniotic injection of ethacridine both for the second trimester induction of labor, mifepristone combined with misoprostol clinical efficacy is better.