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本研究以胃镜、活检作为金标准,对江苏淮安水网平原地区上消化道癌高危人群的食管、胃部疾患进行耳诊筛选试验及其粘膜病变特征的流行病学研究。结果:筛选试验中,食管和胃部疾患的耳诊灵敏度分别为81.92%和82.78%。特异度分别为24.68%和25.31%,阴性预测值分别为71.81%和73.63%。这说明耳诊作为筛选或普查食管和胃部疾患的方法是可行的和有价值的。耳诊对食管、胃癌的诊断试验中,尽管灵敏度均为100%,但其特异度24.08%,26.07%)和阳性预测值(2.65%,3.24%)均偏低。耳诊作为诊断方法,有待进一步提高其特异度。食管和胃部粘膜不同病变的检出率为34.15%,由正常粘膜最终发展成为食管癌、胃癌的转化率分别为2.47%和2.26%,它们与实际食管癌、胃癌的检出率相一致。
In this study, gastroscopy and biopsy as the gold standard, the Huaian plain water area of upper gastrointestinal cancer high risk population of esophageal and gastric disorders ear screening examination and mucosal lesions epidemiological characteristics. Results: Ear screening sensitivity of esophageal and gastric disorders were 81.92% and 82.78% in the screening test respectively. The specificities were 24.68% and 25.31%, respectively. The negative predictive values were 71.81% and 73.63% respectively. This shows that ear diagnosis is feasible and valuable as a method of screening or screening for esophageal and gastric disorders. Ear diagnosis of esophageal and gastric cancer diagnosis, although the sensitivity was 100%, but the specificity of 24.08%, 26.07%) and the positive predictive value (2.65%, 3.24%) were low . Ear diagnosis as a diagnostic method, to be further enhanced its specificity. The detection rate of esophageal and gastric mucosal lesions was 34.15%, and finally from normal mucosa to esophageal cancer, the conversion rates of gastric cancer were 2.47% and 2.26%, respectively, which were correlated with the actual esophageal and gastric cancer The detection rate is consistent.