1981年Siegel 首先提出了“红细胞免疫系统”的新概念,认为红细胞不仅具有运送呼吸气体的功能,更重要的是红细胞膜上存在C_3b 受体,能与C_3b 特异性结合发挥免疫粘附作用.肾病综合征是儿科常见的一种免疫性疾病,其免疫发病机制十分复杂.本文对39例小儿肾病综合征进行了红细胞C_3b 花环率、T 淋巴细胞活性玫瑰花环率测定,探索红细胞免疫功能,T 细胞免疫功能在肾病综合征免疫发病机制方面的作用. In 1981, Siegel first proposed a new concept of “erythrocyte immune system”. He thought that erythrocytes not only have the function of transporting respiratory gases, but more importantly, the presence of C_3b receptors on erythrocyte membrane and specific binding to C_3b to exert immune adherence. Syndrome is a common pediatric immune disease, its immune pathogenesis is very complicated.In this paper, 39 cases of children with nephrotic syndrome erythrocyte C_3b rosette rate, T lymphocyte activity rose rosette rate to explore the immune function of red blood cells, T cells The Role of Immune Function in the Pathogenesis of Nephrotic Syndrome Immune.