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目的 探讨小儿IgA肾病并发急性肾功能衰竭 (ARF)的临床与病理特点。 方法 回顾分析 6例小儿IgA肾病并发ARF的临床与病理资料。 结果 本组IgA肾病患儿并发ARF的发生率占我科同期IgA肾病患儿的 2 3 1% ;ARF好发于学龄期 ,临床表现多为肉眼血尿及大量蛋白尿 ,血肌酐平均为 2 89μmol/L ,病程平均 16天 ,均无需透析治疗即可痊愈 ,病理分级以Ⅱ级为主 ,远期追踪无慢性肾功能不全者。结论 小儿IgA肾病并发ARF发生率不低 ,治疗适当 ,肾功能可以逆转。
Objective To investigate the clinical and pathological features of pediatric IgA nephropathy complicated with acute renal failure (ARF). Methods Retrospective analysis of 6 cases of pediatric IgA nephropathy complicated with ARF clinical and pathological data. Results The incidence of concurrent ARF in children with IgA nephropathy accounted for 21.3% of children with IgA nephropathy in the same period of our department. ARF occurred in school-age. The clinical manifestations were mostly gross hematuria and massive proteinuria with an average serum creatinine of 2 89 μmol / L, the average duration of 16 days, no need for dialysis treatment can be cured, grade Ⅱ-based pathological, long-term follow-up without chronic renal insufficiency. Conclusion The incidence of complicated with IgA nephropathy in children with ARF is not low, appropriate treatment, renal function can be reversed.