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目的:探讨心肌梗死诊断中肌钙蛋白检测的临床价值。方法:从六枝特区人民医院2015年2月-2016年2月的体检者中选出具有代表性的心肌梗死患者与健康体检者各98例,分为观察组和对照组。检测两组体检者血清中肌红蛋白(Mb)、肌酸激酶同工酶(CK-MB)、肌酸激酶(CK)以及心肌肌钙蛋白-I(cTn-I)的指数,并对其进行比较分析。结果:观察组病患与对照组相比,Mb、CK-MB、CK以及cTn-I指数有着显著的提升(P<0.01)。观察组的病患发病后的24 h内,血清中cTn-I、CK和CK-MB指标会到达峰值,12 h内Mb也会到达顶点。观察组与对照组相比,Mb、CK-MB、CK以及cTn-I指数的阳性检出率有着显著的提升,差异具有统计学意义(P<0.05)。通过观察组,阳性减出率指标中,CK最低,MB与MB居中、cTn-I最高,差异具有统计学意义(P<0.05)。结论:体检者如果为心肌梗死,则血清中Mb、CK-MB、CK以及cTn-I的水平也会出现显著提升,通过长期的实践观察,发现cTn-I呈阳性的现象十分普遍。通过对心肌梗死患者血清中cTn-I值的检测,对于病情的诊断有着积极的辅助意义。
Objective: To investigate the clinical value of troponin detection in the diagnosis of myocardial infarction. Methods: A total of 98 patients with typical myocardial infarction and physical examination were selected from the physical examination of People’s Hospital of Liuzhi Special Zone from February 2015 to February 2016, and divided into observation group and control group. The indexes of Mb, CK-MB, CK and cTn-I in the serum of two groups were detected, For comparative analysis. Results: Compared with the control group, Mb, CK-MB, CK and cTn-I index in the observation group were significantly increased (P <0.01). Within 24 hours after the onset of the disease in the observation group, the cTn-I, CK and CK-MB indexes in serum peaked, and Mb reached the apex within 12 h. Compared with the control group, the positive rate of Mb, CK-MB, CK and cTn-I index in the observation group was significantly increased, the difference was statistically significant (P <0.05). Through the observation group, the positive rate of decrease in indicators of CK, MB and MB center, cTn-I highest, the difference was statistically significant (P <0.05). CONCLUSIONS: In the case of myocardial infarction, the levels of Mb, CK-MB, CK and cTn-I in serum also increase significantly. Through long-term practice observation, it is common to find cTn-I positive. Through the detection of serum cTn-I in patients with myocardial infarction, the diagnosis of the disease has a positive secondary meaning.