论文部分内容阅读
目的通过调查丽水口岸出境人员鼠疫F1抗体感染途径及其原因分析,掌握丽水口岸出境人员鼠疫F1抗体阳性人群分布情况。方法从2005年至2012年出境人员留样血清中,随机选择不同年龄的出境人员5 278份血清样本进行鼠疫Fl抗体间接血凝试验;对阳性者进行流行病学调查。结果 5 278份不同年龄的出境人员的血清样本中,采用间接血凝试验检测鼠疫Fl抗体,阳性样本3份,阳性率为0.057%。阳性者中,男性2例,女性1例;年龄最小58岁,最大74岁;对阳性者进行流行病学个案调查,除1例为历史鼠疫幸存者,其他均无明显的临床指征,但都有不同程度蚤类等叮咬史。结论人群血清中鼠疫F1抗体血凝阳性和鼠疫历史疫区有关,并在人血清中检获高滴度鼠疫F1抗体。F1抗体阳性者不一定是现患鼠疫病人,不一定存在传染性,但在鼠疫静息期加强鼠疫F1抗体监测,可对鼠疫感染起到预警作用。
Objective To investigate the distribution of F1 antibody in outpatients in Lishui port by investigating the route of F1 antibody infection in plague outbound from Lishui Port and its causes. Methods From 2005 to 2012, 5 278 serum samples from outpatients leaving China were randomly selected to carry out the indirect hemagglutination test of plague Fl antibody. The epidemiological investigation of positive persons was carried out. Results Serum samples of 5 278 exit-aged people of different ages were tested by indirect hemagglutination test for 3 samples of plague Fl. The positive rate was 0.057%. Among the positives, there were 2 males and 1 females; the youngest was 58 years old and the oldest was 74 years old. There was no obvious clinical indications for the positive cases except one case of historical plague survivors, Have different degrees of bites and other fleas history. Conclusion The blood serum of plague F1 antibody hemagglutination positive and plague epidemic-related, and seized high-titer plague F1 antibody in human serum. F1 antibody-positive patients are not necessarily present plague patients, not necessarily contagious, but in the rest period of plague to enhance the detection of plague F1 antibody, plague infection can play an early warning role.