论文部分内容阅读
背景和目的:本研究总结了英国约克郡激光中心采用支气管镜光动力疗法(PDT)治疗不适合外科手术的早期中央型肺癌患者的临床经验,并对诊断中的问题和 PDT 的适应证进行了讨论。早期中央型肺癌的标准包括支气管镜下可见,可进行细胞学和组织学取样;局限于支气管腔和支气管壁;放射线检查未显示;没有纵隔淋巴结病变或远处转移。从1991年3月至2005年3月,200例中央型肺癌患者接受了支气管镜 PDT 治疗,其中21例(10.5%)符合早期中央型肺癌的入选标准而进入前瞻性研究。全部病例都接受了白光支气管镜检查,最近的12例还进行了自体荧光支气管镜检查。支气管镜 PDT 的指征包括:根治性手术后复发性和
Background and Objective: This study summarizes the clinical experience of bronchoscopic photodynamic therapy (PDT) in patients with early-stage central lung cancer who are unsuitable for surgery at the Yorkshire Laser Center in the United Kingdom. The diagnostic and PDT indications were reviewed discuss. Criteria for early-stage central lung cancer include bronchoscopy, cytological and histological sampling; confinement to the bronchial lumen and bronchial wall; radiographic examination not shown; absence of mediastinal lymph node lesions or distant metastases. From March 1991 to March 2005, 200 patients with central lung cancer received bronchoscopic PDT, and 21 of them (10.5%) met the inclusion criteria of early stage central lung cancer for prospective studies. All cases received white light bronchoscopy, the recent 12 cases were also autofluorescent bronchoscopy. Indications for bronchoscopic PDT include: recurrent and postoperative radical surgery