论文部分内容阅读
有人在40年代设计出口服药理剂量的铁剂(50—250mg或1mg/kg),然后隔一定时间测一次血浆铁,以比较不同制剂的铁吸收,以及食物和药物对铁吸收的干扰作用,由于剂量过大,灵敏性很差,不能鉴别铁缺乏和铁充足状态。然而,用5mg载荷剂的同位素铁作研究,已证明是铁缺乏症的一个灵敏指标。仅仅是贮存铁部分减少的不贫血的正常供血者,他们对铁的吸收远远超过正常铁充足者。这些人只有用小剂量铁耐量试验(Iron tolerance test ITT)方法测定,才能检出,而用其它铁缺乏症的指标检查,则常常是正常的。
Some people in the 40s designed to export pharmacological doses of iron (50-250mg or 1mg / kg), and then measured plasma iron at intervals to compare the iron absorption of different formulations and food and drug interference on iron absorption, Due to overdose and poor sensitivity, iron deficiency and iron adequacy can not be identified. However, studies with isotope iron of 5 mg load have proven to be a sensitive indicator of iron deficiency. Merely storing non-anemic normal blood donors with reduced iron content, they absorb far more iron than normal iron sufficiency. These individuals can only be detected by the Iron tolerance test (ITT) method and are usually normal when examined by other iron deficiency markers.