本文作者综述了不同慢性肝病患者红细胞CR1(ECR1)分子表达与血清可溶性CR1(sCR1)分子的变化 ,并分析其机理。研究指出 ,慢性肝病ECR1分子的数量变化与循环免疫复合物的量呈负相关 ;病毒性慢性肝病患者血清sCR1水平显著升高并与其肝功指标ALT呈显著正相关。对慢性肝病进行sCR1测定对准确了解肝细胞破坏情况和判断预后具有重要价值 The authors reviewed the changes of erythrocyte CR1 (ECR1) molecule expression and serum soluble CR1 (sCR1) molecules in patients with chronic liver disease and analyzed its mechanism. The study indicates that the number of ECR1 molecules in chronic liver disease is inversely correlated with the amount of circulating immune complexes, and the level of serum sCR1 in patients with viral chronic liver disease is significantly increased and positively correlated with its liver function index ALT. The determination of sCR1 in chronic liver disease is of great value in accurately understanding the damage of hepatocytes and in judging the prognosis