兰索拉唑(lansoprazole)为苯并咪唑类衍生物,属于质子泵抑制剂。其分布于胃黏膜壁细胞的酸性环境后,转变为有活性的代谢物。这种代谢物与酸生成部位的H~+-K~+-ATP酶的巯基结合,通过抑制H~+-K~+-ATP酶的活性而抑制酸分泌。主要用于治疗口服疗法不适用的伴有出血的消化性溃疡和预防应激性溃疡。临床常见不良反应主要 Lansoprazole is a benzimidazole derivative, which is a proton pump inhibitor. Its distribution in gastric mucosal cells in the acidic environment, into an active metabolite. This metabolite binds to the thiol group of the H ~ + -K ~ + -ATPase at the acid-forming site and suppresses the acid secretion by inhibiting the activity of the H ~ + -K ~ + -ATPase. Mainly used for the treatment of oral therapy is not applicable with bleeding peptic ulcer and prevention of stress ulcer. Common clinical adverse reactions