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目的探讨超声造影评估颈动脉斑块新生血管预测脑梗死再发的价值。方法对51例初发脑梗死患者行超声造影检查,参考文献对颈动脉斑块进行回声和新生血管分级,随访1年后入选者再发脑梗死情况,应用ROC曲线评估回声和新生血管分级预测脑梗死再发的价值。结果再发脑梗死侧斑块回声分级主要为I级和Ⅱ级,而未再发脑梗死侧主要为Ⅲ级,两组间回声分级差异有统计学意义。再发脑梗死侧斑块新生血管分级主要为Ⅲ级和Ⅳ级,而未再发脑梗死侧主要为I级和Ⅱ级,两组间新生血管分级差异有统计学意义。以新生血管分级>Ⅱ级较以回声分级=I级、=Ⅱ级和<Ⅲ级为标准预测脑梗死再发均具有更好准确率。结论颈动脉斑块新生血管分级是预测脑梗死再发的有效参数,优于回声分级。
Objective To evaluate the value of contrast echocardiography in predicting the recurrence of cerebral infarction after carotid plaque neovascularization. Methods Fifty-one patients with primary cerebral infarction underwent contrast-enhanced ultrasonography. References were made to evaluate the carotid plaques by echogenic and neovascularization. Recurrence of cerebral infarction was assessed one year after follow-up. ROC curve was used to evaluate the echo and neovascular grading The value of recurrent cerebral infarction. Results The echocardiographic grade of recurrent cerebral infarction was mainly grade I and grade II, while the grade of non-recurrent cerebral infarction was grade III. The difference of echo grade between the two groups was statistically significant. Recurrence of cerebral infarction plaque neovascularization grades are mainly grade III and grade IV, but not recurrence of cerebral infarction mainly for grade I and grade II, between the two groups of neovascular grading difference was statistically significant. The neovascularization grade> Ⅱ grade than the echo grade = I grade, = Ⅱ grade and <Ⅲ grade as the standard prediction of cerebral infarction recurrence has a better accuracy. Conclusion Neovascularization of carotid plaque is an effective parameter to predict the recurrence of cerebral infarction, which is better than echo classification.