论文部分内容阅读
目的分析总结宜春市先天性甲状腺功能减低症(CH)筛查、诊疗现状及存在的问题。方法 2013年1月-2015年12月该院对全市156 764例新生儿进行新生儿疾病筛查,对确诊为CH和高促甲状腺激素(TSH)血症患儿分别给予相对应治疗和随访,并对确诊病例进行回顾性分析。结果该市新生儿疾病筛查总体筛查率为70.40%,各地筛查率以丰城最低,为44.69%;其次为宜丰55.83%,再次为铜鼓61.77%。滤纸干血片合格率94.07%,检出CH 114例,高TSH血症60例,CH检出率为1/1 375,明显高于我国的平均发病率1/2 033,为CH高发。病人治疗、随访依从性较差。结论该市CH发病率高可能与地理环境缺碘有关。应提高新生儿疾病筛查率和治疗、随访的依从性,政府职能部门必须加强监督管理,采取适当的医疗保障措施,加大孕期产前宣教力度,同时应加强新生儿筛查专业人员技术培训,提高专业技术水平。
Objective To analyze and summarize the screening, diagnosis and treatment of congenital hypothyroidism (CH) in Yichun City and its existing problems. Methods From January 2013 to December 2015, 156,764 newborns in the city were screened for neonatal disease. The patients with CH and hyper-thyroid hormone (TSH) hyperlipidemia were treated and followed up respectively. Retrospective analysis of the confirmed cases. Results The overall screening rate of neonatal disease screening in the city was 70.40%. The screening rate was 44.69% in Fengcheng, followed by Yifeng 55.83% and again copper drum 61.77%. The pass rate of filter paper dried blood film was 94.07%. There were 114 cases of CH and 60 cases of high TSH. The detection rate of CH was 1/1 375, which was significantly higher than the average morbidity of 1/2 033 in China. Patient treatment, poor follow-up compliance. Conclusion The high incidence of CH in this city may be related to the lack of iodine in geographical environment. The rate of neonatal screening should be improved and compliance with treatment and follow-up should be enhanced. Government departments must step up supervision and administration, take appropriate medical security measures, increase prenatal education during pregnancy, and strengthen technical training for neonatal screening professionals , Improve professional skills.