IgE骨髓瘤是多发性骨髓瘤最罕见的一种。自1967年Johansson等报告第1例以来,至今仅有10例报告。作者在此报告1例,并复习文献,与其他型骨髓瘤进行临床特征的比较。患者男,68岁,因呼吸困难、体重减轻及背痛进行性加重9个月入院。检查见低热、贫血,沿第7～8肋间神经皮肤有带状疱疹。余无异常。血红蛋白 IgE myeloma is the rarest form of multiple myeloma. Since the first case of the Johansson et al. report in 1967, only 10 reports have so far been reported. The author reported 1 case here and reviewed the literature to compare the clinical features with other types of myeloma. The patient male, 68 years old, was admitted for hospitalization for 9 months due to dyspnea, weight loss, and back pain. Check to see low fever, anemia, herpes zoster along the 7th to 8th intercostal nerve skin. I have no exception. Hemoglobin