论文部分内容阅读
Potopne(中译名著罗托品)系含予罂粟科,蓝董科多种植物中的一种生物硷。本文所用系从蓝董科植物攀援指叶紫董又各紫金龙(DactglicPuosScandetlsHutch)根中提出的,我省有丰富的植物资源。研究表明:Protopine具有松驰胃肠道平滑肌,促进胆汁分泌,抗炎,抗肿瘤和抗心律失常等作用。近来发现Protopine同时还具有抑制血小板聚集作用,随着社会人口的高龄化,动脉粥样硬化,冠心病,脑血管意外等心脑血管疾病已成为严重危害人类健康的问题。但由于病因复杂,发病机制至今未完全清楚,临床观察和实验表明:血小板功能异常特别是聚集性异常与这类疾病的发生有十分密切的关系,深入探讨和寻找具有抗血小板作用的药物对于这类疾病的防治有重要意义。而Protopine在这方面有一定的苗头是十分可喜的,值得作进一步的研究。
Potopne (a Chinese translation of the Luotuo Pin) is a biological worm that is contained in various plants of the family Papaveraceae. This article is used from the roots of the blue Dongko plant climber Ye Zidong and each of the Purple Dragon (Dactglic Puos Scandetls Hutch), our province has abundant plant resources. Studies have shown that Protopine has a relaxing gastrointestinal smooth muscle, promoting bile secretion, anti-inflammatory, anti-tumor and anti-arrhythmic effects. Recently, Protopine has also been found to inhibit platelet aggregation. With the aging of the social population, atherosclerosis, coronary heart disease, cerebrovascular accidents and other cardiovascular and cerebrovascular diseases have become serious problems that endanger human health. However, due to complicated etiology, the pathogenesis has not been fully understood. Clinical observation and experiments have shown that abnormal platelet function, especially aggregating abnormalities, is closely related to the occurrence of these diseases. In-depth exploration and search for drugs with anti-platelet effect The prevention and treatment of diseases are of great significance. Protopine has certain signs in this respect. It is very gratifying and worthy of further study.