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目的 对 2 8例成人原发性弥漫性大细胞性 (DLCL)肠非霍奇金淋巴瘤 (NHL)的临床特点、治疗及生存情况进行总结。方法 采用回顾性分析研究。结果 79%的患者接受外科手术联合化疗 ,5 0 %的患者取得CR ,14 %为PR ,3 6%为NR -PD ,中位随访时间 62月 ,7例 ( 2 5 % )患者仍存活 ,3例 ( 11% )患者带瘤生存 ,其余 18例 ( 64 % )患者死亡。结论 本文回顾性了分析 2 8例原发性DLCL肠NHL的临床特征、治疗效果和生存情况 ,外科手术联合化疗为最常见的治疗方式 ,不同治疗策略 ,尤其是外科手术在治疗中的作用尚需前瞻性的随机研究进一步验证。
Objective To summarize the clinical features, treatment and survival of 28 cases of adult primary diffuse large cell (DLCL) enteric non-Hodgkin’s lymphoma (NHL). Methods Using retrospective analysis. RESULTS: Seventy-five percent of patients underwent surgery combined with chemotherapy. CR was achieved in 50% of patients, PR was 14%, NR-PD was 36%, and median follow-up was 62 months. Seven patients (25%) survived, Three patients (11%) survived with tumor and the remaining 18 patients (64%) died. Conclusion This retrospective analysis of 28 cases of primary DLCL intestinal NHL clinical features, treatment and survival, surgical treatment combined with chemotherapy is the most common treatment, different treatment strategies, especially the role of surgery in the treatment of Prospective randomized studies were further validated.