本文研究环孢菌素 A(cyclosporine A,CYA)对类风湿性关节炎(rheumatoid arthritis,RA)患者肾功能的作用,并监测 CYA 和非类固醇抗炎药物(nonsteroidal anti—inflammatory drugs,NSAIDs)联合应用对 RA 患者肾功能的影响。病人和方法本组11例(6男,5女)顽固型 RA 患者,平均年龄53±9岁,已患 RA7.6±5.4年,在停服抗类风湿性药物至少6周后,测定其肾功能基值,并随机分入甲氧萘丙酸(naproxen)治疗组(口服,750mg/d)和苏灵大 This article studies the effect of cyclosporine A (CYA) on renal function in patients with rheumatoid arthritis (RA) and monitors the combination of CYA and nonsteroidal anti-inflammatory drugs (NSAIDs) Application of RA patients with renal function. Patients and methods The group of 11 patients (6 men and 5 women) stubborn RA patients, mean age 53 ± 9 years old, had a RA of 7.6 ± 5.4 years, stopped taking anti-rheumatic drugs for at least 6 weeks after the test The basis of renal function, and randomized into naproxen treatment group (oral, 750mg / d) and Su Ling large