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测定３５例原发性肝癌、３２例肝炎、３２例肝硬化、１０例转移性肝癌、１２例消化道癌肿和３６例健康对照者的血清α－Ｌ－岩藻糖苷酶（ＡＦＵ）和甲胎蛋白（ＡＦＰ）含量，原发性肝癌患者血清ＡＦＵ和ＡＦＰ含量明显高于其他各组（Ｐ＜０．００１）。当把ＡＦＵ的正常上限定为６００ｎｍｏｌ·ｍｌ－１·ｈ－１时，诊断原发性肝癌的敏感性为７７．１４％，特异性为９９．１８％，联合测定ＡＦＵ和ＡＦＰ＃ＦＫ的诊断敏感性达９１．４３％、特异性达９８．３６％，表明ＡＦＵ可以作为原发性肝癌血清学诊断的有用指标。
Determination of serum alpha-L-fucosidase (AFU) and A in 35 cases of primary liver cancer, 32 cases of hepatitis, 32 cases of cirrhosis, 10 cases of metastatic liver cancer, 12 cases of digestive tract cancer and 36 healthy controls The content of AFP and AFP in patients with primary liver cancer was significantly higher than that in other groups (P<0.001). When the normal level of AFU was limited to 600 nmol·ml-1·h-1, the sensitivity of diagnosis of primary liver cancer was 77.14% and the specificity was 99.18%. The diagnosis of AFU and AFP#FK was jointly diagnosed. The sensitivity was 91.43% and the specificity was 98.36%, indicating that AFU can be used as a useful marker for serodiagnosis of primary liver cancer.