皮下植入式输注泵于70年代初首先由Blackshear设计,70年代后期开始用于肝癌的区域化疗.此泵能缓慢、持续向肿瘤区释放化疗药,但不增加系统的药物浓度,携泵患者仍可自由活动,新近临床研究还显示具有较好的治疗效果.由于上述优点,越来越多引起人们的重视,但用泵治疗肝癌的疗效还有待进一步随机前瞻性临床研究. The subcutaneous implantable infusion pump was first designed by Blackshear in the early 1970s, and was used for regional chemotherapy of liver cancer in the late 1970s. This pump can slowly and continuously release chemotherapeutic drugs to the tumor area, but does not increase the system drug concentration, carrying the pump The patient is still free to move, and recent clinical studies have also shown that it has a good therapeutic effect. Due to the above advantages, more and more attention has been given to people, but the efficacy of pump treatment of liver cancer remains to be further randomized prospective clinical studies.