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目的:观察中西医结合治疗缺铁性贫血(IDA)伴幽门螺杆菌(Hp)阳性患者的疗效。方法:将37例IDA伴Hp阳性患者随机分为治疗组21例和对照组16例。对照组给予常规西药治疗,治疗组给予香砂六君子汤加味、右旋糖酐铁片治疗。治疗前后分别检测患者血红蛋白(Hb)、血清铁(S)I、血清铁蛋白(SF)、总铁结合力(TIBC)及尿素酶依赖性试验(14C呼气试验)。结果:治疗组患者经中西医结合治疗后均得到治愈,Hp均转阴,治疗时间短;对照组患者未能全部治愈,Hp未能完全转阴,治疗时间长。2组Hb、SI、SF、TIBC治疗前后比较,差异均有显著性意义(P<0.05);2组治疗后各项指标比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。结论:中西医结合治疗IDA伴Hp阳性患者疗效确切,效果优于单纯西药治疗。
Objective: To observe the treatment of iron deficiency anemia (IDA) with Helicobacter pylori (Hp) -positive patients by integrated traditional Chinese and Western medicine. Methods: Thirty-seven IDA patients with Hp positive were randomly divided into treatment group (21 cases) and control group (16 cases). The control group was given conventional Western medicine, the treatment group was given Xiangsha Liujunzi Decoction, dextran iron tablets treatment. Patients’ hemoglobin (Hb), serum iron (S) I, serum ferritin (SF), total iron binding capacity (TIBC) and urease dependent test (14C breath test) were detected before and after treatment. Results: The patients in the treatment group were cured after the combination of TCM and Western medicine, Hp were both negative and the treatment time was short. The patients in the control group were not cured completely, and Hp failed to turn negative completely and the treatment time was long. There were significant differences in the levels of Hb, SI, SF and TIBC between the two groups before and after treatment (P <0.05). There were significant differences between the two groups after treatment (P <0.05, P < 0.01). Conclusion: Integrative treatment of IDA with Hp-positive patients with exact effect, the effect is better than Western medicine alone.