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目的观察多点注射垂体后叶素在输卵管妊娠腹腔镜保守性手术中减少出血的疗效。方法选择确诊为未破裂且有生育要求的输卵管妊娠患者192例,随机分为两组。研究组104例,应用10%垂体后叶素多点注射于患侧病灶输卵管系膜及同患侧子宫角宫肌处5ml,单极电凝钩切开患侧输卵管肿胀处1～2cm,用吸管吸出绒毛样物混合血凝块。对照组88例,采用传统腹腔镜下输卵管保守性手术。观察两组术中出血量、手术时间及持续性异位妊娠的发生情况等。结果所有手术均在腹腔镜下顺利完成,两组术中出血量、手术时间比较,有显著性差异(P<0.01)。两组持续性异位妊娠发生率比较,差异无统计学意义(P>0.05)。结论输卵管妊娠腹腔镜保守性手术中应用多点注射垂体后叶素可明显减少术中出血,甚至不需电凝创面,缩短了手术时间,有效保护了输卵管组织,值得临床推广。
Objective To observe the curative effect of multiple injection of pituitrin in reducing the hemorrhage in laparoscopic conservative surgery of tubal pregnancy. Methods 192 cases of tubal pregnancy diagnosed as unbroken and fertility were selected and randomly divided into two groups. The study group of 104 cases, the application of 10% pituitrin injection in the affected lesion tubal and ipsilateral lesion uterine horn at 5ml, monopolar coagulation hook cut tubal tubal swelling at 1 ~ 2cm, with Pipette villi mixed blood clots. The control group of 88 cases, the use of traditional laparoscopic tubal conservative surgery. Two groups of intraoperative blood loss, operation time and the occurrence of persistent ectopic pregnancy. Results All the operations were successfully performed in laparoscopic operation. There was a significant difference in bleeding volume and operation time between the two groups (P <0.01). There was no significant difference between the two groups in the incidence of persistent ectopic pregnancy (P> 0.05). Conclusions The application of pituitary injection of pituitrin in conservative surgery of tubal pregnancy can significantly reduce intraoperative bleeding, even without coagulation wound, shortening the operation time and effectively protecting the tubal tissue, which is worthy of clinical promotion.