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为开发有效治疗艾滋病的药物,近年日本学者从世界各地收集传统的天然药物,以抗HIV活性为指标筛选出萜类、黄酮类及多酰胺类等活性成分。本文介绍了活性成分的分子结构及其构效关系的研究。
In order to develop effective drugs for the treatment of AIDS, Japanese scholars have collected traditional natural medicines from various parts of the world in recent years and screened out active ingredients such as steroids, flavonoids, and polyamides as an indicator of their anti-HIV activity. This article describes the molecular structure of active ingredients and their structure-activity relationships.