造血干祖细胞植入造血微环境,并进一步自我更新和增生分化的过程称为造血干细胞的“归巢”。这是一个复杂得多步骤过程,包括干细胞的迁移、黏附,并受各种黏附分子、趋化因子、细胞因子、蛋白酶、附属细胞和造血细胞相互作用的调节,而这个调节机制仍未完全阐明,现就造血干细胞的归巢研究进展作一简要综述。 Hematopoietic stem and progenitor cells into the hematopoietic microenvironment, and further self-renewal and proliferation of differentiation process called hematopoietic stem cells “homing.” This is a complex and multistep process that involves stem cell migration, adhesion, and regulation by the interaction of various adhesion molecules, chemokines, cytokines, proteases, accessory cells, and hematopoietic cells, yet this regulatory mechanism has not been fully elucidated , Now on the research progress of hematopoietic stem cell homing make a brief review.