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如早期工作所指出,淋巴结的检查是含石英粉尘致纤维化的一个很适合的指标。本文报导了对大鼠纵膈淋巴结的研究。雌性大鼠于SiO_2浓度为20毫克/米~3的粉尘管道中吸入染尘,每周5次,每次8小时,实验延续时间为六个月。染尘结束后,立刻处死4只动物(Ⅰ组),4只皮下注射一次PVNO(聚乙烯吡啶氮氧化物)(Ⅱ组),4只留着不予治疗(Ⅲ组)。两个月之后此8只都处死。将淋巴结与肺一起
As early work has pointed out, the examination of lymph nodes is a very suitable indicator of fibrosis caused by quartz dust. This article reports the study of mediastinal lymph nodes in rats. Female rats in the dust concentration of 20 mg / m3 ~ 3 dust inhalation of dust, 5 times a week, each 8 hours, the experimental duration of six months. Four animals (Group I) were sacrificed immediately after the end of the dyed dust. Four mice were injected subcutaneously with PVNO (Polyvinylpyridine Nitrogen Oxide) (Group II) and four were left untreated (Group III). Two months later the eight were executed. The lymph nodes together with the lungs