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目的 利用多普勒超声评价冠心病 (CHD)患者的血管内皮功能。方法 对 3 2例CHD患者和 3 2例正常人肱动脉充气加压及舌下含服硝酸甘油前后血管直径和血流速度变化的检测。结果 CHD患者肱动脉加压前后的血管直径和血流速度变化百分比明显小于正常对照组 ;而舌下含服硝酸甘油前后肱动脉内径及血流速度变化百分比在两组之间无明显差异。结果 CHD患者存在血管内皮功能下降 ,多普勒超声可作为评价血管内皮功能的一种新方法。
Objective To evaluate the vascular endothelial function in patients with coronary heart disease (CHD) by using Doppler ultrasound. Methods The changes of blood vessel diameter and blood flow velocity in brachial artery of 32 CHD patients and 32 normal controls before and after sublingual nitroglycerin were measured. Results The percent change of vessel diameter and blood flow velocity before and after brachial artery compression in CHD patients was significantly lower than that in normal control group. The change of brachial artery diameter and blood flow velocity before and after sublingual nitroglycerin did not show significant difference between the two groups. Results There was a decrease of endothelial function in CHD patients. Doppler ultrasound could be used as a new method to evaluate endothelial function.