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腺嘌呤是一种少见的嘌呤硷,其新陈代谢活跃。外来的80%腺嘌呤很快掺入高能量、并有调节作用的核苷酸和核酸中,约8~20%注射给与的腺嘌呤能转变成8—氧腺嘌呤和2,8,二氧腺嘌呤。这些化合物都是极强的肾毒。用少量腺嘌呤注入血液能维持有高浓度的ATP,保持膜的完整,延长人类红细胞的生存能力。在欧洲通常使用少量的腺嘌呤保存血液,在美国已对腺嘌呤进行毒理及代谢方面的研究,非经肠道的腺嘌呤已用来治疗粒性白细胞缺乏症。在一些临床实验研究中用口服非常高剂量的腺嘌呤来治疗
Adenine is a rare purine, its metabolism is active. Exogenous 80% adenine soon incorporates high-energy, and regulatory nucleotides and nucleic acids, about 8-20% of the adenine injected for injection into 8-oxo-adenine and 2,8, Oxydenine. These compounds are extremely nephrotoxic. A small amount of adenine into the blood can maintain a high concentration of ATP, to maintain the integrity of the membrane, to extend the viability of human red blood cells. In Europe, a small amount of adenine is commonly used to preserve blood. In the United States, adenine has been studied for toxicological and metabolic studies. Non-intestinal adenine has been used to treat granulocytic leukemia. In some clinical trials with oral administration of very high doses of adenine to treat