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目的分析卡贝缩宫素预防妊娠期高血压产妇剖宫产术后出血的效果。方法选取妊娠期高血压产妇160例,随机均分为观察组与对照组。观察组剖宫产后给予卡贝缩宫素宫肌底内注射;对照组剖宫产后给予缩宫素宫肌底内注射。比较两组产妇产后出血量及分娩结局。结果观察组剖宫产术后24h内出血量低于对照组[(360.5±179.7)ml vs.(486.3±298.3)ml](P<0.05);两组新生儿体重、1-min Apgar评分差异无统计学意义(P>0.05)。观察组产后血压无明显下降1例,经降压治疗后好转。对照组恶心、呕吐2例,血压波动在142/90~150/95mmHg之间,经降压治疗后趋于稳定。结论卡贝缩宫素能有效地控制妊娠期高血压产妇剖宫产术后的出血量,无严重不良反应发生。
Objective To analyze the effect of carbetocin in preventing bleeding after cesarean section in hypertensive pregnant women. Methods 160 pregnant women with hypertension during pregnancy were randomly divided into observation group and control group. The observation group was given intramuscular injection of carbetoc Palace after cesarean section; the control group was injected intramuscularly with oxytocin after cesarean section. Postpartum hemorrhage and delivery outcomes were compared between the two groups. Results The intra-abdominal bleeding volume within 24 hours after cesarean section in the observation group was lower than that in the control group [(360.5 ± 179.7) ml vs. (486.3 ± 298.3) ml] (P <0.05) Statistical significance (P> 0.05). Observation group postpartum blood pressure was no significant decline in 1 case, after treatment by antihypertensive improved. In the control group, nausea and vomiting occurred in 2 cases. The blood pressure fluctuated between 142/90 and 150/95 mmHg, and stabilized after antihypertensive treatment. Conclusions Carbetocin can effectively control the amount of bleeding after cesarean section in hypertensive pregnant women without serious adverse reactions.