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甘露醇广泛用于诊断和预防急性少尿性肾衰竭及治疗急性脑水肿。急性呼吸窘迫综合征和青光眼,也用以预防透析时急剧渗透克分子浓度变化。当静脉输入甘露醇后它不能通过细胞膜。仍然以相同的浓度在细胞间液和血浆中以其渗透的活性作用使细胞内的水分向细胞外间隙转移。
Mannitol is widely used in the diagnosis and prevention of acute oliguric renal failure and treatment of acute cerebral edema. Acute respiratory distress syndrome and glaucoma are also used to prevent drastic osmolality changes during dialysis. It does not pass through the cell membrane when mannitol is given intravenously. Still with the same concentration in the intercellular fluid and plasma with its permeability of the role of the intracellular water to the extracellular space transfer.