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目的 观察糖化低密度脂蛋白 (Gly-LDL)与糖尿病并发颈动脉粥样硬化 (CAS)的关系。方法 确诊 型糖尿病 (DM2 )并发 CAS32例。对照组 30例。采用微柱亲和层析法测定血浆 Gly-LDL 含量。结果 DM2并发 CAS组 Gly-L DL水平为 (8.89±2 .5 0 ) %。对照组 Gly-LDL水平为 (4.0 5± 1.0 8) %。 DM2并发 CAS组 Gly-L DL水平显著高于对照组 (P<0 .0 1) ,且颈动脉狭窄率与Gly-LDL含量呈正相关 (P<0 .0 1)。结论 Gly-L DL水平与 DM2患者动脉粥样硬化 (AS)形成有密切关系。
Objective To investigate the relationship between Gly-LDL and carotid atherosclerosis (CAS). Methods Diagnosed diabetes (DM2) complicated with CAS32 cases. Control group of 30 cases. Plasma micro-LDL levels were determined by micro-column affinity chromatography. Results The level of Gly-L DL in DM2 complicated CAS group was (8.89 ± 2.50)%. Gly-LDL level in the control group was (4.05 ± 1.08)%. The level of Gly-L DL in DM2 complicated CAS group was significantly higher than that in control group (P <0.01), and the carotid artery stenosis rate was positively correlated with the content of Gly-LDL (P <0.01). Conclusion The level of Gly-L DL is closely related to the formation of atherosclerosis (AS) in DM2 patients.