HBV感染首先累及肝脏。HBV相关抗原—抗体的免疫复合物可引起肝外器官损害,肾脏是肝外受累主要脏器之一,临床称为HBV免疫性肾小球肾炎,简称(HBV-GN)。它是一种慢性隐匿性疾病,据统计资料表明,儿童发病率明显高于成年人,成人发病年龄平均为35岁,男性高于女性。本病预后较好,儿童患者30％～60％可自行缓解,但成人的缓解率明显低于儿童。 HBV infection first affects the liver. HBV-related antigen - antibody immune complexes can cause extrahepatic organ damage, the kidneys are extrahepatic involvement of one of the major organs, clinically known as HBV immune glomerulonephritis, referred to as (HBV-GN). It is a chronic occult disease, according to statistics show that the incidence of children was significantly higher than that of adults, the average age of onset of adult 35-year-old, men than women. The prognosis of this disease is better, 30% to 60% of children can relieve themselves, but the response rate of adults was significantly lower than children.