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目的:检查孕妇绒毛巨细胞病毒(CMV)感染,了解孕妇CMV的早期感染状况。方法:采用ELISA、PCR、病毒分离方法检测32例早孕妇女血清CMV-IgM、宫颈和绒毛CMV-DNA。结果:孕妇血清CMV-IgM阳性率9.38%(3/32);宫颈CMV-DNA阳性率为12.5%(4/32);绒毛CMV-DNA阳性1例,分离阳性1例,阳性率为6.25%(2/32);2例绒毛CMV感染,但血清及宫颈检查正常。结论:妊娠早期绒毛的CMV感染率为6.25%,母亲血清和宫颈检查正常并不能排除胎儿先天感染的可能。
Objective: To examine the infection of CMV in pregnant women and to understand the early infection status of CMV in pregnant women. Methods: Serum CMV-IgM, cervical and chorionic CMV-DNA in 32 early pregnant women were detected by ELISA, PCR and virus isolation methods. Results: The positive rate of CMV-IgM in pregnant women was 9.38% (3/32), the positive rate of CMV-DNA in cervix was 12.5% (4/32), the positive CMV-DNA was found in 1 case, positive in CMV-IgM The rate was 6.25% (2/32). Two cases of chorionic villus CMV infection, but the serum and cervical examination was normal. Conclusion: The CMV infection rate in early pregnancy is 6.25%. The normal serum and cervix in mother can not rule out the possibility of congenital infection of fetus.