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目的探讨糖尿病合并冠心病患者血清缺血修饰白蛋白(IMA)、尿微量白蛋白(UMalb)水平与心功能的相关性及临床意义。方法测定60例糖尿病合并冠心病患者IMA与UMalb,分析其与心功能之者间的关系。结果 IMA、UMalb均随着心功能Ⅰ、Ⅱ、Ⅲ、Ⅳ级患者级别的升高逐渐升高(P<0.05)。与治疗前相比,治疗后各级IMA均下降(P<0.05);心功能Ⅰ、Ⅱ级患者UMalb治疗后下降(P<0.05)。结论糖尿病合并冠心病患者IMA、UMalb水平与心功能具有相关性。
Objective To investigate the correlation between serum creatinine (IMA), urinary albumin (UMalb) level and cardiac function in patients with diabetes mellitus complicated with coronary heart disease and its clinical significance. Methods The IMA and UMalb in 60 patients with diabetes mellitus complicated with coronary heart disease were measured and their relationship with cardiac function was analyzed. Results The IMA and UMalb levels gradually increased with the increase of patients with cardiac function Ⅰ, Ⅱ, Ⅲ and Ⅳ (P <0.05). Compared with those before treatment, the levels of IMA decreased at all levels after treatment (P <0.05). The scores of UMalb in patients with grade I and II decreased after treatment (P <0.05). Conclusion There is a correlation between the levels of IMA and UMalb in diabetic patients with coronary heart disease and cardiac function.