编辑同志: 看了你刊1976年4、5期合刊中《注射青霉素第三针发生过敏性休克》一文,对如何正确使用青霉素有很大启发。现仅就文中的一些问题,提出自己的一点看法。患儿为啥注射第三针后才出现青霉素过敏性休克呢?第三针注射液是第二针注射时余下后放置室内已有数个小时。青霉素溶解四个小时后再用,不但其效价要减低,而且会产生青霉素衍生物,如青霉烯酸、青霉烯胺等,这一类衍生物是产生过敏的重要物 Edit comrades: read you published in 1976 4,5 combined issue of “injection of penicillin in the third needle anaphylactic shock” article on how to properly use penicillin great inspiration. Now just some of the issues in the text, put forward their own point of view. Why children with penicillin anaphylactic shock after the injection of the third needle? The third needle injection is the second injection after the rest of the room has been placed indoors for several hours. Penicillin dissolved four hours before use, not only its potency to reduce, but also produce penicillin derivatives, such as penicillin, penicillin amine, this type of derivative is an important allergic reaction