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关于“7591”治疗矽肺的效果,我們于1958年和1959年先后作了报告。在54例各期矽肺患者中,根据临床症状、呼吸功能及X綫所見,初步地肯定了“7591”的有效作用。国內各地也在采用这一疗法。我們使用这一疗法已有四年多,对这一疗法的效果应再作一次評价。治疗矽肺的效果最好是按下列三項評定:(1)X线所見病变規律性发展的停止或緩慢;(2)临床自觉及他觉症状的消失或好轉;(3)劳动能力包括呼吸功能的恢复或改善。很多学者认为,矽肺的危害主要在于积存于机体的二氧化矽尘粒不断水解而成胶体矽酸,后者是引起纤維增生病变的原因。我們設想:“7591”对矽肺的良好作用主要是由于它能和引起矽肺的物质(矽酸)起化学作用,矽酸变为不能引起纤維化的物貭而被排出体外,于是矽肺病变停止发展,早期
On the “7591” effect of treatment of silicosis, we have reported in 1958 and 1959 successively. In 54 cases of silicosis patients, according to clinical symptoms, respiratory function and X-ray findings, initially affirmed the “7591” effective. This therapy is also being used throughout China. We have been using this therapy for more than four years and should evaluate the effect of this therapy again. The best treatment of silicosis according to the following three assessment: (1) X-ray findings of the regular development of the disease to stop or slow; (2) clinical symptoms and his symptoms disappeared or improved; (3) working capacity, including respiratory function Recovery or improvement. Many scholars believe that the harm of silicosis mainly lies in the continuous hydrolysis of silica dust accumulated in the body into colloidal silicon acid, which is the cause of fibrosis. We hypothesize that the good effect of “7591” on silicosis is mainly due to its chemical interaction with the silicic acid-causing substance (silicic acid), which is excreted when it becomes incapable of causing fibrosis and ceases to develop Early