先天性甲状腺功能低下症,一般被称为克汀病,在临床上也称为呆小病。克汀病在新生儿期一般无明显症状,既便有症状也是非特异性的,在早期作出诊断是很困难的。甲状腺激素的早期缺乏,可造成不可逆性智力障碍。所以,早期发现,早期治疗是极为重要的。现就近年来日本关于克汀病及其周围疾病的研究现状,加以介绍。 Congenital hypothyroidism, commonly known as cretinism, is also known as ailment in the clinic. Cretinism in the neonatal period generally no obvious symptoms, even if the symptoms are non-specific, in the early diagnosis is very difficult. The early lack of thyroid hormone can cause irreversible mental retardation. Therefore, early detection, early treatment is extremely important. In recent years, Japan on the status of cretinism and its disease research, to be introduced.