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CD14是一种膜锚着糖蛋白 ,可作为内毒素的主要受体 ,激活巨噬细胞释放前炎症因子 ,引发炎性级联反应。另一方面 ,CD14作为巨噬细胞识别清除凋亡细胞的受体之一 ,介导凋亡细胞的非炎性清除
CD14 is a membrane-anchored glycoprotein that acts as a major endotoxin receptor that activates macrophages to release proinflammatory cytokines and trigger an inflammatory cascade. CD14, on the other hand, recognizes macrophages as one of the receptors that clear apoptotic cells and mediates the non-inflammatory clearance of apoptotic cells