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目的:分析荆门地区2013年药品不良反应(ADR)发生特点,为进一步做好ADR监测工作提供参考。方法:收集荆门地区2013年各报告单位上报国家药品不良反应监测中心的ADR报告1 926份,统计分析报告单位、患者年龄性别分布、不良反应类型、药品种类、结果评价等项目。结果:1 926例ADR报告中,医疗机构的报告占98.7%;静脉滴注引起的ADR占83.6%;抗感染药物引起的ADR占52.7%,其中以头孢菌素类发生的ADR最多;引起的皮肤及附件的ADR最多,占37.2%;市中心评价结果为很可能的ADR最多,占54.3%。结论:各报告单位要重视ADR监测工作,增强ADR上报的主动性、准确性。
Objective: To analyze the characteristics of adverse drug reaction (ADR) in Jingmen area in 2013 and provide reference for further monitoring of ADR. Methods: A total of 1 926 ADR cases were collected from all the reporting units in the national drug adverse reaction monitoring center in Jingmen area in 2013, and statistical analysis units, patient age and sex distribution, types of adverse reactions, types of drugs and results evaluation were collected. Results: Of the 926 ADR cases, 98.7% were reported by medical institutions; 83.6% were caused by intravenous drip; 52.7% were ADRs caused by anti-infective drugs, of which cephalosporins produced the most ADRs; The highest ADR was found in skin and appendages, accounting for 37.2%. The most likely ADR in downtown was 54.3%. Conclusion: All reporting units should attach importance to ADR monitoring and enhance the initiative and accuracy of ADR reporting.