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目的:评价氨酚羟考酮片治疗中重度腰腿痛的疗效和安全性。方法:将76例中重度腰腿痛患者随机分为治疗组和对照组,每组均为38例。治疗组给予口服氨酚羟考酮片,对照组给予布洛芬缓释胶囊治疗。结果:对总体疗效而言,两组总有效率分别为91.18%和80.00%,总体疗效及改善重度疼痛患者VAS评分等的差异有统计学意义(P<0.05)。临床观察中未发现氨酚羟考酮片有何明显的毒副作用和不良反应。结论:氨酚羟考酮片治疗中重度腰腿痛安全有效,值得在临床上推广应用。
Objective: To evaluate the efficacy and safety of paracetamol and oxycodone tablets in the treatment of moderate and severe low back pain. Methods: 76 cases of moderate and severe low back pain were randomly divided into treatment group and control group, with 38 cases in each group. The treatment group was given oral oxycodone oxycodone tablets, while the control group was given ibuprofen sustained release capsules. Results: The total effective rate of the two groups was 91.18% and 80.00%, respectively. The overall effect and VAS score of patients with severe pain were significantly different (P <0.05). Clinical observation did not find any significant side effects and adverse reactions of oxycodone tablets. Conclusion: Oxycodone tablets of paracetamol are safe and effective in the treatment of moderate and severe low back pain, which is worth popularizing in clinic.