目的　探讨无创通气治疗慢性阻塞性肺疾病 (COPD)并 型呼衰的临床应用价值。方法　对 2 8例慢性阻塞性肺疾病 (COPD)并 型呼衰患者采用 Bi PAP呼吸机经口鼻面罩正压通气 ,观察治疗前后血气分析的p H、Pa O2 、Pa CO2 、Sa O2 指标变化。结果　无创通气后 Pa O2 、Sa O2 均明显升高 ,Pa CO2 明显降低 ,p H明显改善 ,差异均有显著性 (P<0 .0 1)。结论　 Bi PAP呼吸机经口鼻面罩无创通气治疗慢性阻塞性肺疾病 (COPD)并 型呼衰疗效满意 ,无明显并发症 ,值得临床推广应用。 Objective To investigate the clinical value of noninvasive ventilation in treating chronic obstructive pulmonary disease (COPD) and respiratory failure. Methods 28 patients with chronic respiratory failure (COPD) and type 1 respiratory failure were treated with Bi PAP ventilator. The changes of p H, Pa O2, Pa CO2 and Sa O2 in blood gas analysis before and after treatment were observed . Results After noninvasive ventilation, Pa O2, Sa O2 were significantly increased, Pa CO2 was significantly reduced, p H significantly improved, the difference was significant (P <0.01). Conclusions Bi PAP ventilator is effective in treating chronic obstructive pulmonary disease (COPD) and respiratory failure by oral or nasal mask noninvasive ventilation without obvious complication and is worthy of clinical application.