以病例对照研究方法探讨系统性红斑狼疮（ＳＬＥ）发生的有关危险因素。单因素分析表明：与ＳＬＥ有关的危险因素是初婚年龄、经量异常、扁桃体经常发炎、喜欢食糖、居住环境潮湿；多因素Ｌｏ－ｇｉｓｔｉｃ分析则提示居住环境潮湿、经量异常、喜欢食糖为ＳＬＥ危险因素。居住楼房可视为预防因素。各因素间无交互作用。 A case-control study was conducted to investigate the risk factors associated with systemic lupus erythematosus (SLE). Univariate analysis showed that the risk factors related to SLE were the age at first marriage, abnormal menstruation, frequent amygdala, like sugar and humid living environment. The multi-factor Lo-gistic analysis suggested that the living environment was wet and had abnormal amount of sugar, Risk factors. Residential buildings can be considered as a preventative factor. No interaction between factors.