论文部分内容阅读
目的：探讨肾细胞癌伴单发转移灶病例的治疗方法。方法：回顾性分析1986～2003年肾癌伴单发转移和肾癌根治术后复发单个转移共51例病人的临床资料。除2例脑转移行放疗外,49例均行转移灶的外科切除辅以干扰素治疗。结果：17例肾癌根治及转移灶切除(1例放疗)治疗,总的平均生存期26．3个月。34例复发单个转移灶手术切除(1例放疗)后,总的平均生存期为41．9个月。肾癌根治切除术后复发转移间期在1年内的,转移灶切除后平均生存30．5个月,超过1年复发转移的为61．8个月(P＜0．05)。肝和脑转移灶术后疗效较其他部位的转移灶预后差。结论：时肾癌伴单发转移和根治术后复发单个转移应行肾癌及转移灶的外科切除,可延长生存期；1年以上复发转移间期的疗效较好。
Objective: To investigate the treatment of renal cell carcinoma with single metastasis. Methods: The clinical data of 51 patients with single metastasis of renal cell carcinoma with single metastasis and radical recurrence of renal cell carcinoma from 1986 to 2003 were retrospectively analyzed. In addition to 2 cases of brain metastasis and radiation therapy, 49 patients underwent surgical resection combined with interferon therapy. Results: 17 cases of radical nephrectomy and resection of metastases (one case of radiotherapy) were treated with a mean overall survival of 26.3 months. After a total of 34 recurrent single tumor resections (1 case of radiotherapy), the overall mean survival was 41.9 months. The recurrence and metastasis after radical resection of renal cell carcinoma in 1 year, the average survival after resection of the metastasis 30.5 months, more than 1 year recurrence and metastasis was 61.8 months (P <0.05). Liver and brain metastases after surgery than other parts of the metastasis prognosis is poor. Conclusions: Surgical resection of renal cell carcinoma and metastasis of renal cell carcinoma with single metastasis and single metastasis after radical surgery should prolong the survival time. The recurrence and metastasis more than one year is better.