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目的观察腹腔镜手术与注射用醋酸曲普瑞林联合治疗子宫内膜异位症的临床疗效。方法 120例子宫内膜异位症腹腔镜术后患者随机分为2组:试验组组(腹腔镜手术联合注射用醋酸曲普瑞林,40例)和对照组(腹腔镜手术联合孕三烯酮,80例)。试验组肌肉注射醋酸曲普瑞林3.75 mg,每28 d注射1次,连用6个月;对照组于手术后月经来潮第1 d,开始口服孕三烯酮2.5 mg,每周2次,连续3～6个月,比较2组疗效及不良反应。结果试验组显效率高于对照组,而复发率低于对照组,但差异均无统计学意义(P>0.05);2组排卵时间的恢复分别为(18.32±6.86),(21.81±6.07)d,试验组明显少于对照组(P<0.05)。痤疮、体重增加、胃肠道反应等不良反应,试验组明显高于对照组(P<0.05)。结论腹腔镜术后联合注射用醋酸曲普瑞林治疗子宫内膜异位症疗效确切。
Objective To observe the clinical efficacy of laparoscopic surgery combined with triptorelin acetate in the treatment of endometriosis. Methods One hundred and twenty cases of endometriosis after laparoscopic surgery were randomly divided into two groups: experimental group (laparoscopic surgery combined with triptorelin acetate injection, 40 cases) and control group (laparoscopic surgery combined with gestrin Ketone, 80 cases). Test group intramuscular injection of triptorelin acetate 3.75 mg, once every 28 d injection, once every 6 months; control group in the menstrual cramps on the first day after surgery, started gestrinone 2.5 mg, twice a week, continuous 3 to 6 months, compared two groups efficacy and adverse reactions. Results The effective rate of the test group was significantly higher than that of the control group, but the recurrence rate was lower than that of the control group (P> 0.05). The ovulation time of the two groups were (18.32 ± 6.86), (21.81 ± 6.07) d, the experimental group was significantly less than the control group (P <0.05). Acne, weight gain, gastrointestinal reactions and other adverse reactions, the experimental group was significantly higher than the control group (P <0.05). Conclusion Laparoscopic surgery combined with triptorelin acetate for the treatment of endometriosis is effective.