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用沙鼠脑缺血及再灌注动物模型,研究因缺血后再灌注不同时期周围血白细胞计数和分类,脑实质中小胶质细胞和白细胞数的变化规律.发现周围血白细胞数在再灌注4小时开始升高,至再灌注12小时达到高峰,以中性粒细胞数增多为主;再灌注4小时脑实质中小胶质细胞数增至最多,白细胞则于再灌注24小时增多最为明显。
The model of cerebral ischemia and reperfusion in gerbils was used to study the changes of microglial cells and white blood cells in brain parenchyma after different stages of ischemia and reperfusion. Found that the number of peripheral blood leukocytes began to rise 4 hours after reperfusion to peak 12 hours after reperfusion, with an increase in the number of neutrophils; 4 hours after reperfusion, the number of microglia in brain parenchyma increased to the most, Reperfusion 24 hours increased the most obvious.