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目的探讨三联疗法根除幽门螺杆菌(Hp)对慢性胃炎(CG)的治疗效果。方法选择我院收治的CG患者92例,随机将92例患者分为研究组与对照组,每组46例。对照组患者口服兰索拉唑治疗,研究组在此基础上联合克拉霉素与阿莫西林治疗。结果研究组治疗的总有效率为95.65%,明显高于对照组的78.26%(P<0.05)。研究组Hp根除率为97.83%,高于对照组的82.61%(P<0.05)。研究组不良反应发生率为8.70%,对照组不良反应发生率为6.52%,两组对比差异无显著性(P>0.05)。结论通过三联疗法根除Hp对CG作用显著,可以有效改善患者的临床症状,安全可靠,应用方便,适于临床广泛推广。
Objective To investigate the therapeutic effect of triple therapy on chronic gastritis (CG) eradicated by Helicobacter pylori (Hp). Methods Ninety-two CG patients admitted to our hospital were randomly divided into two groups: study group and control group, with 46 cases in each group. Patients in the control group were treated with lansoprazole, and the study group was treated with clarithromycin and amoxicillin on this basis. Results The total effective rate of the study group was 95.65%, which was significantly higher than that of the control group (78.26%, P <0.05). The study group Hp eradication rate was 97.83%, 82.61% higher than the control group (P <0.05). The incidence of adverse reactions was 8.70% in the study group and 6.52% in the control group. There was no significant difference between the two groups (P> 0.05). Conclusions Hp eradication through triple therapy has a significant effect on CG, which can effectively improve the clinical symptoms of patients. It is safe, reliable and easy to use. It is suitable for clinical promotion.