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报道2例首发症状分别为尿崩症、眼外肌麻痹的鞍区肿瘤病例,经手术治疗,病理诊断为垂体区转移癌,其原发肿瘤为肺癌,术后预后不良。对出现尿崩症、眼外肌麻痹、视力明显下降、垂体功能低下症状而年龄较大的患者,当MRI检查蝶鞍区有不规则呈侵蚀性生长肿物时,应首先考虑垂体区恶性肿瘤的诊断,并检查有无原发癌肿。对于诊断不明者可考虑手术探查,以明确诊断及缓解症状,对于一般情况差已有广泛转移者不主张手术治疗
Two cases of saddle tumors with initial symptoms of diabetes insipidus and extraocular muscle paralysis were reported. After surgical treatment, the pathological diagnosis was metastatic cancer in the pituitary gland. The primary tumor was lung cancer, and the prognosis was poor. In older patients with diabetes insipidus, extraocular muscle paralysis, decreased visual acuity, and hypopituitarism, when an MRI scan has an irregular, aggressive growth mass in the sellar region, the pituitary area malignancy should be considered first. The diagnosis and check for primary cancer. For undiagnosed persons, surgical exploration may be considered to confirm the diagnosis and relieve symptoms. For those who have poor general conditions, they have not accepted surgical treatment.