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目的:观察中西医结合预防性治疗老年带状疱疹后遗神经痛临床疗效。方法:对80例老年带状疱疹患者进行回顾性分析,A组40例给予阿昔洛韦治疗,B组40例给予复方当归注射液联合阿昔洛韦治疗。比较2组治疗前后的视觉模拟疼痛评分(VAS)、止疱时间、后遗神经痛发生率、疼痛症状消失时间、减轻时间及并发症发生情况。结果:B组止疱时间、后遗神经痛发生率、疼痛症状消失时间及减轻时间等均低于A组(P<0.05)。2组患者治疗前、治疗后第1周的VAS评分比较,差异无统计学意义(P>0.05),但B组治疗后第2周、3周、4周的VAS评分均低于A组患者,差异均有统计学意义(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:复方当归注射液联合阿昔洛韦治疗老年带状疱疹,可有效预防后遗神经痛的发生,显著减轻疼痛症状、缩短疼痛缓解及消失时间,安全性高。
Objective: To observe the clinical curative effect of prophylactic treatment of senile herpes zoster neuralgia by integrated traditional Chinese and western medicine. Methods: 80 elderly patients with herpes zoster were retrospectively analyzed. A group of 40 patients were treated with acyclovir and 40 patients of group B were given Fufang Danggui injection combined with acyclovir. Visual analog pain score (VAS), blister time, incidence of post-nociceptive pain, disappearance of pain symptom and time and complications were compared between the two groups before and after treatment. Results: B group blister time, the incidence of postherpetic neuralgia, the disappearance of pain symptoms and reduce the time were lower than the A group (P <0.05). There was no significant difference in VAS score between the two groups before treatment and the first week after treatment (P> 0.05). However, the VAS scores of the second, third and fourth weeks after treatment in group B were lower than those in group A , The differences were statistically significant (P <0.05). The incidence of adverse reactions in the two groups, the difference was not statistically significant (P> 0.05). Conclusion: Compound Danggui injection combined with acyclovir in the treatment of elderly herpes zoster, which can effectively prevent the occurrence of post-natal neuralgia, significantly reduce the pain symptoms, shorten the pain relief and disappearance of time, high safety.