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鼻咽癌分化差、恶性度高,易于转移和侵犯邻近组织。咽旁间隙(Parapharyngeal space)与鼻咽腔密切相邻,极易受侵犯。过去由于常规X线颅底照片的分辨率不高,偶可见咽旁模糊致密影,但常待出现有关颅神经症状才能断诊,因而咽旁间隙侵犯的检出率很低。本院1974年报告鼻咽癌放射治疗的702例中,有后组颅神经症状者仅10例(1.42％)。本文将就咽旁间隙侵犯的诊断、疗效差的原因和合理的放射治疗设计进行探讨。
Nasopharyngeal carcinoma has poor differentiation and high degree of malignancy, and it is easy to metastasize and invade neighboring tissues. The parapharyngeal space is closely adjacent to the nasopharyngeal cavity and is vulnerable to infringement. In the past, due to the low resolution of conventional X-ray skull base photographs, even close to the parapharyngeal blur was observed, but craniocerebral symptoms are often required to be diagnosed. Therefore, the detection rate of parapharyngeal space invasion is very low. Of the 702 cases reported by the hospital in 1974 for radiotherapy for nasopharyngeal carcinoma, only 10 cases (1.42%) had posterior cranial nerve symptoms. This article will discuss the diagnosis of parapharyngeal space violations, the causes of poor efficacy, and the rational design of radiation therapy.